GHK is a tripeptide of glycine, histidine and lysine. GHK-Cu is its complex with a copper ion, and the distinction between the two is not cosmetic. Sold as research material, not as a medicine.
Bio-Peptide, 100 mg
210,00 złAdd to cart5 in stock (can be backordered)
What is in the vial
Bio-Peptide is the only manufacturer offering GHK-Cu here, in a 100 mg vial. That is a large vial next to the peptides in the growth hormone group, and it reflects how this molecule is used: in far larger amounts per application than a secretagogue. A 100 mg vial with 5 ml of bacteriostatic water gives 20 mg per millilitre. The arithmetic is in the guide on reconstitution.
The copper complex is also what gives the solution its blue colour, which is worth knowing before you decide something has gone wrong with the vial.
What the research describes
Reviews describe GHK-Cu increasing collagen and elastin synthesis, the formation of blood vessels and the migration of fibroblasts. In a rat wound study, GHK alone produced no effect, while a statistically significant increase in collagen deposition appeared only with the copper complex. The activity is attributed to the complex, not to the bare tripeptide.
That is the reason the name matters when buying. A product labelled GHK is not the same thing as GHK-Cu, and in the study above the difference was the difference between an effect and none.
The limits, from the same reviews
Tripeptides have a half-life below roughly 30 minutes in plasma. Peptide-metal complexes are unstable, because copper is highly reactive and sensitive to environmental conditions. Skin absorption is poor because the molecule is strongly hydrophilic, and after intradermal administration roughly 95 percent is cleared quickly.
Percentage claims about collagen growth circulate in cosmetic marketing. We do not repeat them, because we could not trace them to a primary publication.
Where it sits in this catalogue
GHK-Cu is listed in the skin and longevity group with NAD+ and glutathione. The three share a category and a buyer, not a mechanism, and what the human evidence supports for each is compared in the guide on NAD and glutathione injections. The place of copper peptides among cosmetic peptides is described in peptides in skincare.
Status
Not an approved medicine. It appears in cosmetic formulations, where the concentrations and the route of application are entirely different from an injectable solution. We publish no dosing schedules.
Handling and verification
Supplied as lyophilised powder. Given the instability of copper complexes, storage discipline matters more here than average: see storage. Check the code under the hologram and the batch certificate as described in check your product. We ship within Poland and abroad; outside Poland the cost is quoted individually, depending on weight and destination country. Details: shipping and payments.
Questions
Is GHK the same as GHK-Cu?
No. GHK-Cu is the complex with a copper ion, and in the rat wound study the effect appeared only with the copper complex.
Why is the solution blue?
Because of the copper in the complex. It is a property of the molecule, not a sign of contamination.
Does it absorb through the skin?
Poorly. The molecule is strongly hydrophilic, which is what the reviews give as the reason.
What about the collagen percentages quoted in advertising?
We do not repeat them, because we could not trace them to a primary publication.