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Semaglutide is a GLP-1 receptor agonist, the single-receptor molecule of the incretin group. In registered form it is a prescription medicine; what is sold here is research material, not a medicine.

What is in the vial

Bio-Peptide is the only manufacturer offering semaglutide here, in a 3 mg vial of lyophilised powder. That is a small vial by the standards of this catalogue, and it is small for a reason: the registered medicine is dosed in milligrams per week, not per injection. A 3 mg vial with 1.5 ml of bacteriostatic water gives 2 mg per millilitre. The arithmetic and the conversion into insulin syringe units are in the guides on reconstitution and syringe units.

What the trials showed

In obesity trials, semaglutide at 2.4 mg once weekly reduced body weight by roughly 15 percent over about two years, against 2 to 3 percent on placebo, in people with obesity or overweight without diabetes. In the only head-to-head trial against tirzepatide, SURMOUNT-5, it reached 13.7 percent over 72 weeks against 20.2 percent for tirzepatide.

The dose is escalated gradually to limit side effects, which are dominated by the digestive tract: nausea, vomiting, diarrhoea and constipation.

Status, stated plainly

Semaglutide is sold as a medicine under the names Ozempic, approved for type 2 diabetes, and Wegovy, approved for obesity and for overweight with comorbidities. Both are prescription-only. A vial of research material is not those products: it lacks their manufacturing controls, their dose and their product information. Comparison of the three incretin molecules is in the comparison guide.

Why these medicines are prescription-only rather than available over the counter is a question with a specific answer, and it is set out in the guide on prescription status. In short: the dose escalation, the contraindications and the monitoring are part of the treatment, not paperwork around it.

Where it sits among the incretins

Tirzepatide acts on two receptors and beat semaglutide in the only head-to-head trial; retatrutide acts on three and has finished phase 3 without approval anywhere. Semaglutide is the one with the longest record and the largest body of published data. How the three differ mechanically is explained in the incretin guide.

Handling and verification

Supplied as lyophilised powder. Storage rules change once it is dissolved: see storage. Check the code under the hologram and the batch certificate as described in check your product. We ship within Poland and abroad; outside Poland the cost is quoted individually, depending on weight and destination country. Details: shipping and payments.

Questions

Is this the same as Ozempic or Wegovy?

No. Those are registered medicines with a known dose, pharmaceutical quality control and product information. This is research material.

How much weight did semaglutide produce in trials?

Roughly 15 percent over about two years at 2.4 mg weekly, against 2 to 3 percent on placebo, in people with obesity or overweight without diabetes.

How does it compare with tirzepatide?

In SURMOUNT-5, the only head-to-head trial, 13.7 percent against 20.2 percent over 72 weeks.

What are the common side effects?

Gastrointestinal: nausea, vomiting, diarrhoea and constipation. The dose is escalated gradually in the registered products to limit them.