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CJC-1295, 10 mg. CJC-1295 is a synthetic analogue of growth hormone releasing hormone that stimulates the pituitary receptor for that hormone.

What is in the pack

It is the largest CJC-1295 pack in this catalogue, at the same price per milligram as the 5 mg vials, and also the one that stands longest in solution once opened. Nouveaux Ltd. supplies this product as a dual-chamber cartridge: 10 mg of freeze-dried powder in one chamber and 1 ml of solvent in the other. The chambers are joined just before first use, so no liquid has to be moved from one container to another. After activation with the included millilitre the solution stands at 10 mg per millilitre, which is 100 mcg per unit on a U-100 syringe.

The conversion of an amount into insulin syringe units is worked through in the guide on syringe units, and the rules that change once the powder is dissolved are in storage.

Nouveaux Ltd. as the manufacturer

Nouveaux Ltd. has the narrowest catalogue of the three and the largest packs: BPC-157 20 mg, CJC-1295 10 mg, sermorelin 10 mg, PEG-MGF 10 mg and follistatin 2 mg are all exclusive to this brand here. A larger pack also stands longer once dissolved, which is the trade-off to weigh before ordering.

What the evidence says

The often quoted half-life of 5.8 to 8.1 days was measured on the form with DAC, not on this one. This version acts briefly and is meant to imitate the body's own pulses. The full account, with the sources and the limits, is on the CJC-1295 page, and the background in the guide on CJC-1295 with DAC or without.

We publish no dosing schedules. Sold as research material, not as a medicine.

This is the largest CJC-1295 pack without DAC in the catalogue, twice the content of the 5 mg versions from the other two brands. Nouveaux Ltd. also fills the DAC form in 10 mg and the ready mixes with ipamorelin and the GHRP peptides.

Concentration in this cartridge

Total liquid Concentration Per unit on a U-100 syringe
1 ml 10 mg/ml 100 mcg
2 ml 5 mg/ml 50 mcg
5 ml 2 mg/ml 20 mcg

The table is arithmetic and nothing else: it converts the 10 mg in this cartridge into the concentration for a given total volume of liquid. The 1 ml row is the cartridge as supplied, after the chambers are joined; the other rows show what further dilution would give. It is not a dosing recommendation, and we publish none.

This cartridge next to the CJC-1295 vials

The same compound is sold here in two other versions: Bio-Peptide, 5 mg and Genheal, 5 mg. The molecule is identical in each; what differs is the manufacturer and the amount in the pack. This is the largest of the 3 packs, at the same price per milligram as the other two, and the one that stands longest in solution.

Also from Nouveaux Ltd. in this group

Within Growth hormone peptides, Nouveaux Ltd. also supplies CJC-1295 with DAC 10 mg, GHRP-2 10 mg and GHRP-2 and CJC-1295 10 mg.

Why short action can be a choice, not a flaw

The body does not keep growth hormone at a steady level. It releases it in bursts spread over the day, with the largest one at night, after falling asleep. A short-acting peptide fits into that rhythm instead of replacing it.

The version without DAC occupies the GHRH receptor in a narrow window around the injection and then gives way. The result is a short pulse of growth hormone rather than a level held for many days. Anyone who sees the physiological rhythm as important chooses this form and accepts more frequent administration, so a pack is used up faster than with the DAC version.

CJC-1295 without DAC and Mod GRF 1-29

In practice the two names describe the same way of working: a short-acting GHRH analogue without the albumin-binding linker. The differences come down to the naming used by manufacturers and to pack sizes. Both names appear in our range, so compare above all the milligrams in the pack and the form it comes in.

State of knowledge and status

Human data for CJC-1295 are very limited. They come down to one phase 1 study from 2006, and there are no completed phase 2 or phase 3 trials for either form. The peptide is not an approved medicine in the United States. On the World Anti-Doping Agency list it is in category S2, prohibited at all times, including out of competition.

The cartridge in practice

The Nouveaux Ltd. pack is a dual-chamber cartridge: 10 mg of powder in one chamber and 1 ml of solvent in the other. The chambers are joined just before first use, so nothing has to be transferred between containers. After activation the solution stands at 10 mg per millilitre, or 100 mcg per unit on a U-100 syringe, twice the concentration of a 5 mg vial dissolved in the same volume. Let it dissolve on its own, without shaking, and keep the activated cartridge in the fridge at 2 to 8 degrees Celsius, away from light.

Who this cartridge is for

You want short action and the largest pack of CJC-1295 without DAC in the catalogue: this is the one. You want to choose the concentration yourself: the Bio-Peptide box holds 5 mg with two ampoules. You would rather inject once a week: take CJC-1295 with DAC.

A GHRH analogue allows a lower GHRP dose: a 1996 study

Peptides from the GHRP group raise growth hormone strongly, but along with it also prolactin and cortisol, depending on the dose. A study from December 1996 in the Journal of Clinical Endocrinology and Metabolism showed how to get around this. The researchers tested hexarelin in healthy adult men, alone and together with growth hormone-releasing hormone.

What was given Growth hormone Prolactin Cortisol
Hexarelin alone, rising doses a rise with a plateau at higher doses a rise of about 180 percent a dose-dependent rise
GHRH with a small dose of hexarelin a large pulse a moderate rise no rise

The conclusion is a practical one. The rise in cortisol is linked to the size of the GHRP dose rather than being an inherent feature of the peptide. Adding a GHRH analogue gives a large growth hormone pulse without the need to raise the GHRP dose.

What a GHRH analogue gives on its own

In a 1997 study from Turin, six healthy young adults received GHRH, GHRP-2 or hexarelin intravenously on separate days. At the same dose per kilogram of body weight, both GHRP peptides gave a higher growth hormone pulse than GHRH. So a GHRH analogue alone acts more gently, and in a pair it strengthens the other peptide.

This cartridge contains 10 mg of CJC-1295 without DAC, a short-acting GHRH analogue. The studies above concerned natural GHRH, not CJC-1295, and they show how the pair works. All the GHRH analogues are set side by side in the guide Sermorelin, Mod GRF 1-29, CJC-1295 and tesamorelin.

Sources: Massoud et al., Journal of Clinical Endocrinology and Metabolism 1996, Arvat et al., Peptides 1997.

Questions

How much CJC-1295 is in this cartridge?

10 mg of lyophilised powder from Nouveaux Ltd., in a dual-chamber cartridge with 1 ml of solvent.

What concentration does the included millilitre give?

10 mg per millilitre, which is 100 mcg per unit on a U-100 insulin syringe. Other volumes are in the table above.

Is this the same molecule as the Bio-Peptide vial?

Yes. CJC-1295 is the same compound in every pack here. The difference is the manufacturer and the amount: 10 mg in this one against 5 mg in that one.

Verification and delivery

Every pack carries a code under the hologram and comes from a batch with a certificate of analysis; how to check both is described in check your product. We ship within Poland and abroad. Outside Poland shipping costs 30 EUR paid in advance or 80 EUR cash on delivery, the same for every country: shipping and payments.