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PEG-MGF, 10 mg. PEG-MGF is mechano growth factor with polyethylene glycol attached, a construct that does not occur in the body and that clears far more slowly than unmodified MGF.

What is in the pack

It is the largest PEG-MGF pack in this catalogue, which makes it the cheapest per milligram and also the one that stands longest in solution once opened. Nouveaux Ltd. supplies this product as a dual-chamber cartridge: 10 mg of freeze-dried powder in one chamber and 1 ml of solvent in the other. The chambers are joined just before first use, so no liquid has to be moved from one container to another. After activation with the included millilitre the solution stands at 10 mg per millilitre, which is 100 mcg per unit on a U-100 syringe.

The conversion of an amount into insulin syringe units is worked through in the guide on syringe units, and the rules that change once the powder is dissolved are in storage.

Nouveaux Ltd. as the manufacturer

Nouveaux Ltd. has the narrowest catalogue of the three and the largest packs: BPC-157 20 mg, CJC-1295 10 mg, sermorelin 10 mg, PEG-MGF 10 mg and follistatin 2 mg are all exclusive to this brand here. A larger pack costs less per milligram, and it also stands longer once dissolved, which is the trade-off to weigh before ordering.

What the evidence says

Pegylation is a pharmacokinetic argument, not evidence of an effect. No completed randomised trial of administering either form had been published as of April 2026. The full account, with the sources and the limits, is on the PEG-MGF page, and the background in the guide on MGF and PEG-MGF.

We publish no dosing schedules. Sold as research material, not as a medicine.

This is the largest PEG-MGF pack in the catalogue, 10 mg against the 5 mg the other two brands fill. Nouveaux Ltd. does not list unmodified MGF at all, so from this brand the pegylated form is the only version of the molecule.

Concentration in this cartridge

Total liquid Concentration Per unit on a U-100 syringe
1 ml 10 mg/ml 100 mcg
2 ml 5 mg/ml 50 mcg
5 ml 2 mg/ml 20 mcg

The table is arithmetic and nothing else: it converts the 10 mg in this cartridge into the concentration for a given total volume of liquid. The 1 ml row is the cartridge as supplied, after the chambers are joined; the other rows show what further dilution would give. It is not a dosing recommendation, and we publish none.

This cartridge next to the PEG-MGF vials

The same compound is sold here in two other versions: Bio-Peptide, 5 mg and Genheal, 5 mg. The molecule is identical in each; what differs is the manufacturer and the amount in the pack. This is the largest of the 3 packs, which makes it the cheapest per milligram and the one that stands longest in solution.

Also from Nouveaux Ltd. in this group

Within Muscle peptides, Nouveaux Ltd. also supplies ACE-031 10 mg, Follistatin 344 2 mg and IGF-1 LR3 1 mg.

What pegylation does

Polyethylene glycol, PEG for short, is a chemically inert polymer attached to drug molecules and peptides. It makes the molecule larger and slows its removal from the circulation. It has no biological action of its own and does not change what the peptide binds to.

The effect is purely pharmacokinetic: the same molecule stays available for longer. With MGF, whose natural form breaks down in body fluids within minutes, that difference decides whether working with the peptide is practical at all. The extension potentially reaches days and depends on the size of the attached PEG molecule.

An important distinction: PEG-MGF does not occur in the body. Natural MGF is made from the IGF-1 gene under mechanical load, while the pegylated version is a construct made in a laboratory.

What the data show and what they do not

Human data are limited to observational studies measuring the body's own MGF expression after exercise, which is something quite different from the effect of giving the peptide from outside. One independent laboratory also found no proliferative effect on primary human myoblasts. Claims of a local action on damaged muscle fibres, easy to find in sales copy, have no support in these data.

The cartridge in practice

The Nouveaux Ltd. pack is a dual-chamber cartridge: 10 mg of powder in one chamber and 1 ml of solvent in the other. The chambers are joined just before first use, so nothing has to be transferred between containers. After activation the solution stands at 10 mg per millilitre, or 100 mcg per unit on a U-100 syringe, twice the concentration of a 5 mg vial dissolved in the same volume. Let it dissolve on its own, without shaking, and keep the activated cartridge in the fridge at 2 to 8 degrees Celsius, away from light.

Who this cartridge is for

You want PEG-MGF with nothing to prepare and the largest pack of it here: this is the one. You measure small portions and want a fine scale: the Bio-Peptide box holds 5 mg with two ampoules. You would rather have the molecule without pegylation: take MGF.

MGF beyond muscle: studies of bone and cartilage

The end fragment of MGF, called the E peptide, has also been studied in bone and cartilage. This work is less known than the debate over muscle growth, but it gives concrete numbers from animal models.

Study Model Result
Deng et al., International Orthopaedics 2011 bone-forming cells and 27 rabbits with a defect in the radius the E peptide stimulated the proliferation of bone-forming cells 1.4 times more strongly than IGF-1, and a higher dose sped up healing of the defect
Luo et al., Biomaterials 2015 silk scaffolds with MGF in a joint cartilage defect in rabbits cell recruitment up to 1.8 and 2 times stronger than with TGF-beta3, a better score for the rebuilt cartilage
Cui et al., Journal of Molecular Endocrinology 2014 rat bone marrow stem cells no effect on proliferation, an effect on cell migration and differentiation

A picture emerges from these papers of a factor that acts on repair cells in several tissues. In bone it stimulated bone-forming cells more strongly than IGF-1, and in cartilage it drew cells to the site of the defect. In bone marrow stem cells it did not increase their number, but changed their movement and maturation.

All three papers concern animals or cells, and in the cartilage paper MGF was built into a special scaffold. These are not studies of PEG-MGF given by injection, and there are no human studies. PEG-MGF is on the WADA list in group S2, banned at all times. More in the guide MGF and PEG-MGF.

Sources: Deng et al., International Orthopaedics 2011, Luo et al., Biomaterials 2015, Cui et al., Journal of Molecular Endocrinology 2014.

Questions

How much PEG-MGF is in this cartridge?

10 mg of lyophilised powder from Nouveaux Ltd., in a dual-chamber cartridge with 1 ml of solvent.

What concentration does the included millilitre give?

10 mg per millilitre, which is 100 mcg per unit on a U-100 insulin syringe. Other volumes are in the table above.

Is this the same molecule as the Bio-Peptide vial?

Yes. PEG-MGF is the same compound in every pack here. The difference is the manufacturer and the amount: 10 mg in this one against 5 mg in that one.

Verification and delivery

Every pack carries a code under the hologram and comes from a batch with a certificate of analysis; how to check both is described in check your product. We ship within Poland and abroad. Outside Poland shipping costs 30 EUR paid in advance or 80 EUR cash on delivery, the same for every country: shipping and payments.